Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10911393 | Lung Cancer | 2011 | 5 Pages |
Abstract
The current results showed that these alterations in gene or protein expression can account for all resistant mechanisms. This phenomenon suggests the existence of complicated relationships among acquired resistance-related genes.
Keywords
EGR-1L858RT790MTKITTPEGFRp-AktPI 3-kinaseAdenocarcinomaIHCimmunohistochemicalstable diseasecomputed tomographyEMTRECISTTime to progressionLung cancerphosphatidylinositol-3-kinaseResponse Evaluation Criteria in Solid TumorsAcquired resistanceTyrosine kinase inhibitorPartial responsecomplete responsePtenEpithelial–mesenchymal transitionEpidermal growth factor receptor
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Authors
Hidetaka Uramoto, Hidehiko Shimokawa, Takeshi Hanagiri, Michihiko Kuwano, Mayumi Ono,