Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10911480 | Lung Cancer | 2012 | 8 Pages |
Abstract
Higher expression of EphA2 and ephrin-A1 was more related to the female sex, reduced smoking status, adenocarcinoma, well differentiated carcinomas, p-stage IA, and EGFR gene mutations. Higher EphA2 mRNA expression in p-stage I NSCLC patients was positively related to improved prognoses. These results may reflect a tumor suppressive role for the EphA2/ephrin-A1 system in a population of patients restricted to p-stage I NSCLC.
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Authors
Masashi Ishikawa, Ryo Miyahara, Makoto Sonobe, Marika Horiuchi, Toshi Mennju, Ei Nakayama, Masashi Kobayashi, Ryutaro Kikuchi, Jiro Kitamura, Naoto Imamura, Cheng-Long Huang, Hiroshi Date,