| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10913825 | Matrix Biology | 2013 | 10 Pages |
Abstract
⺠Thrombospondin-1, an inhibitor of angiogenesis, is methylated in several malignancies. ⺠Pharmacologic reversal of methylation can inhibit angiogenesis in malignant melanoma. ⺠Knockdown of TSP-1 enhances melanoma angiogenesis in a xenograft model.
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Authors
Daniel J. Lindner, Yan Wu, Rebecca Haney, Barbara S. Jacobs, John P. Fruehauf, Ralph Tuthill, Ernest C. Borden,