| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10913844 | Matrix Biology | 2012 | 9 Pages |
Abstract
⺠Leiomyoma tissue exhibited an increased pseudo-dynamic modulus compared to myometrium. ⺠Altered viscoelastic properties contributed significantly to the stiffness of leiomyoma. ⺠Leiomyoma cells exhibited an attenuated response to applied cyclic strain. ⺠Leiomyoma cells had reduced levels of active RhoA after mechanical stimulation or LPA treatment. ⺠Leiomyoma cells responded abnormally to variation in substrate stiffness.
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Authors
John M. Norian, Carter M. Owen, Juan Taboas, Casey Korecki, Rocky Tuan, Minnie Malik, William H. Catherino, James H. Segars,