Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10913849 | Matrix Biology | 2012 | 7 Pages |
Abstract
⺠We examined the mineralization processes in Abcc6â/â mice, a model system for PXE, by energy dispersive X-ray, and Fourier transform infrared imaging spectroscopy (FT-IRIS). ⺠The principal components of the mineral deposits were calcium and phosphate. ⺠Determination of the mineral phases by FT-IRIS suggested progressive maturation of the mineral deposits from amorphous calcium phosphate to hydroxyapatite. ⺠These results provide critical information of the mechanisms of mineralization in PXE, with potential pharmacologic implications.
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Authors
N. Beril Kavukcuoglu, Qiaoli Li, Nancy Pleshko, Jouni Uitto,