Article ID Journal Published Year Pages File Type
10913850 Matrix Biology 2012 8 Pages PDF
Abstract
► Sulfatases play an important role in alveolar formation and lung function. ► We identified that over accumulation of sulfated glycosaminoglycans leads to upregulation of TGFβ signaling. ► Anti-TGFβ therapy leads to normal lung development and function in Sumf1−/− mice.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Authors
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