Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10913850 | Matrix Biology | 2012 | 8 Pages |
Abstract
⺠Sulfatases play an important role in alveolar formation and lung function. ⺠We identified that over accumulation of sulfated glycosaminoglycans leads to upregulation of TGFβ signaling. ⺠Anti-TGFβ therapy leads to normal lung development and function in Sumf1â/â mice.
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Authors
Emilio Arteaga-Solis, Carmine Settembre, Andrea Ballabio, Gerard Karsenty,