| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10913952 | Matrix Biology | 2005 | 10 Pages |
Abstract
In conclusion, our data show that phenotypic changes of transdifferentiating HSC and induction of matrix synthesis are independent processes, the latter being stimulated by both, Smad dependent and MAPK dependent TGF-β signaling.
Keywords
ECMTGF-βMyofibroblast-like cellsSMADsMFBp38FCSECLTSPα-SMASECHSCHepatocytesMAPKenhanced chemiluminescencetransforming growth factor-βThrombospondinDexamethasonefetal calf serumKupffer cellsSinusoidal endothelial cellsHepatic stellate cellsFibrosisExtracellular matrixmitogen activated protein kinaseLiver
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Authors
Susanne Lindert, Lucia Wickert, Iris Sawitza, Eliza Wiercinska, Axel M. Gressner, Steven Dooley, Katja Breitkopf,