| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10914519 | Molecular Oncology | 2016 | 13 Pages |
Abstract
Our results highlight SLC18A2 as a new promising methylation marker candidate for PC diagnosis. Furthermore, SLC18A2 expression (RNA and protein) showed promising prognostic potential beyond routine clinicopathological variables. Thus, novel SLC18A2-based molecular tests could have useful future applications for PC detection and identification of high-risk patients.
Keywords
SLC18A2quantitative methylation-specific PCRqMSPCRPCMPCBCRPSATCGATMALMDFFPEThe cancer genome atlasROC analysisReceiver operating characteristic analysisDiagnosisRadical prostatectomyProstate cancerMetastatic prostate cancerCastration-resistant prostate cancerBiochemical recurrenceformalin-fixed paraffin-embeddedlaser capture microdissectionTissue microarrayProstate intraepithelial neoplasiahazard ratioBiomarkersBenign prostatic hyperplasiaBPHprognosisPIN
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Authors
Christa Haldrup, Anne-Sofie Lynnerup, Tine Maj Storebjerg, Søren Vang, Peter Wild, Tapio Visakorpi, Christian Arsov, Wolfgang A. Schulz, Johan Lindberg, Henrik Grönberg, Lars Egevad, Michael Borre, Torben Falck Ãrntoft, Søren Høyer,