Article ID Journal Published Year Pages File Type
10914722 Molecular Oncology 2013 11 Pages PDF
Abstract
► How genetically engineered mouse models have been used to address the role of MYC in tumour initiation and maintenance. ► How subtle changes in levels of MYC can influence downstream signalling and thus tumourigenesis. ► Summary of ongoing efforts to target endogenous MYC, both genetically and with novel therapies.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Authors
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