Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10914722 | Molecular Oncology | 2013 | 11 Pages |
Abstract
⺠How genetically engineered mouse models have been used to address the role of MYC in tumour initiation and maintenance. âºÂ How subtle changes in levels of MYC can influence downstream signalling and thus tumourigenesis. ⺠Summary of ongoing efforts to target endogenous MYC, both genetically and with novel therapies.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Jennifer P. Morton, Owen J. Sansom,