| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10914727 | Molecular Oncology | 2015 | 5 Pages |
Abstract
Cancer treatment is slowly shifting from an approach in which the tissue of origin and the histology were the guiding principles for the choice of chemotherapy towards a genotype-centric approach in which the changes in the cancer genome are used to select patients for treatment with highly selective and targeted drugs. This transition has all the hallmarks of a disruptive innovation and requires major adjustments in the way that cancer is diagnosed and treated. We discuss here the hurdles on the road ahead to a more personalized treatment of cancer.
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Authors
Thomas Tursz, Rene Bernards,