Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10914786 | Molecular Oncology | 2015 | 11 Pages |
Abstract
We have identified a novel, biologically relevant microRNA signature that stratifies high- and low-risk patients in glioblastoma. MicroRNA/mRNA interactions identified within the signature point to novel regulatory networks. This is the first study to formulate a survival risk score for glioblastoma which consists of microRNAs associated with glioblastoma biology and/or treatment response, indicating a functionally relevant signature.
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Authors
Josie Hayes, Helene Thygesen, Charlotte Tumilson, Alastair Droop, Marjorie Boissinot, Thomas A. Hughes, David Westhead, Jane E. Alder, Lisa Shaw, Susan C. Short, Sean E. Lawler,