Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10914842 | Molecular Oncology | 2014 | 15 Pages |
Abstract
By establishing the dual role of osteoblast-borne S1P on both osteoblastic differentiation and CaP cell proliferation and survival, we uncover the importance of S1P in the bone metastatic microenvironment, which may open a novel area of study for the treatment of CaP bone metastasis by targeting S1P.
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Authors
Leyre Brizuela, Claire Martin, Pauline Jeannot, Isabelle Ader, Cécile Gstalder, Guillaume Andrieu, Magalie Bocquet, Jean-Michel Laffosse, Anne Gomez-Brouchet, Bernard Malavaud, Roger A. Sabbadini, Olivier Cuvillier,