Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10914867 | Molecular Oncology | 2014 | 13 Pages |
Abstract
Finally, using quantitative reverse transcriptase PCR and immunohistochemistry (IHC) we identified the TPM3-NTRK1 rearrangement in a CRC clinical sample, therefore suggesting that this chromosomal translocation is indeed a low frequency recurring event in CRC and that such patients might benefit from therapy with TRKA kinase inhibitors.
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Authors
Elena Ardini, Roberta Bosotti, Andrea Lombardi Borgia, Cristina De Ponti, Alessio Somaschini, Rosaria Cammarota, Nadia Amboldi, Laura Raddrizzani, Andrea Milani, Paola Magnaghi, Dario Ballinari, Daniele Casero, Fabio Gasparri, Patrizia Banfi,