Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10914889 | Molecular Oncology | 2013 | 15 Pages |
Abstract
⺠There is an urgent need to develop a novel conceptual framework for the treatment of HNSCC. ⺠The biological robustness of HNSCC was analyzed through a somatic evolution model. ⺠This model well explains the mechanism of “escaping from oncogene addiction”. ⺠We discuss about the possible approaches to target vulnerability of evolving HNSCC.
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Authors
Muneyuki Masuda, Satoshi Toh, Takahiro Wakasaki, Masumi Suzui, Andrew K. Joe,