| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10914893 | Molecular Oncology | 2013 | 18 Pages |
Abstract
⺠APPL2 protein levels are elevated in 40% cases of glioblastoma multiforme. ⺠Overexpression of APPL2 exhibits cytoprotective effects in glioma cells. ⺠APPL2 depletion reduces survival and transformation abilities of glioma cells. ⺠Silencing of APPL2 promotes expression of proapoptotic genes HRK and UNC5B.
Keywords
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Authors
Beata Pyrzynska, Magdalena Banach-Orlowska, Marta Teperek-Tkacz, Katarzyna Miekus, Grazyna Drabik, Marcin Majka, Marta Miaczynska,