Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10914911 | Molecular Oncology | 2012 | 8 Pages |
Abstract
⺠Without certainty on the functionality of an drug target clinical studies should not be started. ⺠We need to try to predict Drug-Registration in the earliest clinical studies. ⺠The most important biomarker is the patient selection biomarker. ⺠Get the pharmacology right before moving on. ⺠Choices on drug combinations should be based on biological rationales.
Keywords
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Authors
Jaap Verweij, Maja de Jonge, Ferry Eskens, Stefan Sleijfer,