| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10914953 | Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 2013 | 8 Pages |
Abstract
- 3-Nitrobenzanthrone formed dG-C8-N-ABA and dG-N2-C2-ABA as major adducts.
- The DNA repair system was less efficient at removing dG-N2-C2-ABA.
- dG-C8-N-ABA blocked DNA replication markedly.
- TLS across dG-C8-N-ABA resulted in a significantly increased mutation frequency.
Keywords
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Authors
Masanobu Kawanishi, Yoshihiro Fujikawa, Hiroshi Ishii, Hiroshi Nishida, Yuka Higashigaki, Takaharu Kanno, Tomonari Matsuda, Takeji Takamura-Enya, Takashi Yagi,