| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10915082 | Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 2005 | 13 Pages |
Abstract
Our results revealed a correlation between micronucleus induction in hepatocytes and hepatocarcinogenicity. This technique can be useful for the detection of micronucleus-inducing chemicals that require metabolic activation, and it enables simultaneous comparison of the micronucleus-inducing potential of chemicals in the liver and peripheral blood in the same individual.
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Authors
Hiroshi Suzuki, Naohiro Ikeda, Kazuo Kobayashi, Yukari Terashima, Yasushi Shimada, Takayoshi Suzuki, Toshiyuki Hagiwara, Shigeki Hatakeyama, Koko Nagaoka, Junichi Yoshida, Yukiko Saito, Jin Tanaka, Makoto Hayashi,