Article ID Journal Published Year Pages File Type
10915826 Nuclear Medicine and Biology 2016 8 Pages PDF
Abstract
In situ NEP/ACE-inhibition diversely affected the in vivo profile of 99mTc-radioligands based on different-length gastrins. Truncated [99mTc]DG4 exhibited overall the most attractive profile during combined NEP/ACE-inhibition in mouse models, providing new opportunities for CCK2R-expressing tumor imaging in man with SPECT.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Preview
99mTc-labeled gastrins of varying peptide chain length: Distinct impact of NEP/ACE-inhibition on stability and tumor uptake in mice
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