| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10915830 | Nuclear Medicine and Biology | 2016 | 17 Pages |
Abstract
In vitro studies show that l-[18F]5 is a good and specific substrate of hIDO, while presenting a very low efflux. These results confirm that l-[18F]5 could be a very useful PET radiotracer for IDO expressing cells in cancer imaging.
Related Topics
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Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Jean Henrottin, Christian Lemaire, Dominique Egrise, Astrid Zervosen, Benoit Van den Eynde, Alain Plenevaux, Xavier Franci, Serge Goldman, André Luxen,
![First Page Preview: Fully automated radiosynthesis of N1-[18F]fluoroethyl-tryptophan and study of its biological activity as a new potential substrate for indoleamine 2,3-dioxygenase PET imaging Fully automated radiosynthesis of N1-[18F]fluoroethyl-tryptophan and study of its biological activity as a new potential substrate for indoleamine 2,3-dioxygenase PET imaging](/preview/png/10915830.png)