Improved production and processing of 89Zr using a solution target

The BMLT-2 target allowed doubling of the beam current for production of 89Zr, resulting in a greater than 2-fold increase in production yield in comparison with a conventional liquid target. The new one-pot synthesis of hydroxamate resin provides a simpler synthesis method for the 89Zr trapping resin. Finally, phosphate buffer elutes the 89Zrfrom the hydroxamate resin in high efficiency while at the same time providing a more biocompatible medium for subsequent use of 89Zr.