Detection of breast cancer microcalcification using 99mTc-MDP SPECT or Osteosense 750EX FMT imaging

This study provides evidence of the accessibility of HAP within the breast tumor microenvironment as an in vivo imaging target for bone-seeking agents. SPECT imaging using 99mTc-MDP can be rapidly translated to the clinic. FMT imaging using Osteosense 750EX is not currently approved for clinical use and is limited to animal research.