| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10915888 | Nuclear Medicine and Biology | 2015 | 9 Pages |
Abstract
18Â F-SFB was the optimal labeling method for Zn-DPA and Cy7-Zn-DPA with respect to radiochemistry and provided complexes with high target-to-background ratios. 18Â F-FB-Zn-DPA and 18Â F-FB-Cy7-Zn-DPA appeared to have a completely different internalization mechanism, while Zn-DPA showed higher binding affinity than Cy7-Zn-DPA. Based on these favorable characteristics, 18Â F-FB-Zn-DPA and 18Â F-FB-Cy7-Zn-DPA should be further evaluated as potential imaging agents for viral infection.
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Authors
Junling Li, Rachael L. Gerlach, Colleen B. Jonsson, Brian D. Gray, Koon Y. Pak, Chin K. Ng,