| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10915918 | Nuclear Medicine and Biology | 2015 | 10 Pages |
Abstract
[18Â F]AMG 580 is a selective and potent PDE10A PET tracer with excellent specific striatal binding in non-human primates. It warrants further evaluation in humans.
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![Radiosynthesis and initial characterization of a PDE10A specific PET tracer [18Â F]AMG 580 in non-human primates](/preview/png/10915918.png "First Page Preview: Radiosynthesis and initial characterization of a PDE10A specific PET tracer [18Â F]AMG 580 in non-human primates")
Authors
Dah-Ren Hwang, Essa Hu, Jennifer R. Allen, Carl Davis, James Treanor, Silke Miller, Hang Chen, Bingzhi Shi, Tanjorie K. Narayanan, Olivier Barret, David Alagille, Zhigang Yu, Mark Slifstein,