Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10915947 | Nuclear Medicine and Biology | 2015 | 9 Pages |
Abstract
The results of this study indicate that imaging of AR availability in rat brain with [18F]FDHT PET is not feasible. The low AR expression in the brain, the rapid metabolism of [18F]FDHT in rats and the poor brain penetration of the tracer likely contributed to the poor performance of [18F]FDHT PET in this study.
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Authors
M.A. Khayum, J. Doorduin, I.F. Antunes, C. Kwizera, R. Zijlma, J.A. den Boer, R.A.J.O. Dierckx, E.F.J. de Vries,