| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10916005 | Nuclear Medicine and Biology | 2014 | 8 Pages |
Abstract
68Ga-DOTA-NGR was easily synthesized and showed favorable biodistribution and kinetics. 68Ga-DOTA-NGR could also specifically bind to the APN receptor in vitro and in vivo, and might be a potential molecular probe for the noninvasive detection of APN-positive tumors and neovasculature.
Keywords
PBS%ID/gNGR peptideMECNAPNHEPESDOTACD13NgRTFA2-[4-(2-hydroxyethyl)-1-piperazinyl]ethanesulfonic acidBSAbovine serum albuminAminopeptidase Ntumor angiogenesisAcetonitrileTrifluoroacetic acidPositron emission tomographyPhosphate buffered salinePETPost-injectionhigh performance liquid chromatographyHPLC
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Authors
Jun Zhang, Xiaoli Lu, Nan Wan, Zichun Hua, Zizheng Wang, Hongbo Huang, Min Yang, Feng Wang,