Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10916013 | Nuclear Medicine and Biology | 2014 | 7 Pages |
Abstract
This is the first report to demonstrate the impact of the multi-targeted Aurora B kinase inhibitor, TAK-901 on tumor FLT uptake. The findings provide a strong rationale for the evaluation of FLT-PET as an early biomarker of tumor response in the early phase clinical development of this compound.
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Authors
Carleen Cullinane, Kelly L. Waldeck, David Binns, Ekaterina Bogatyreva, Daniel P. Bradley, Ron de Jong, Grant A. McArthur, Rodney J. Hicks,