| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10916035 | Nuclear Medicine and Biology | 2014 | 5 Pages |
Abstract
The Zag domain prolonged the circulation time of VHH by reducing the blood clearance of the labeled fusion protein 67Ga-NOTA-VHH-Zag. In this way, the anti-TNF VHH in fusion with the Zag ABD presents a higher therapeutic potential than the unmodified VHH.
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Authors
MaurÃcio Morais, Cátia Cantante, Lurdes Gano, Isabel Santos, Sara Lourenço, Catarina Santos, Carlos Fontes, Frederico Aires da Silva, João Gonçalves, João D.G. Correia,