| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10916056 | Nuclear Medicine and Biology | 2013 | 6 Pages |
Abstract
99mTc-HABBN SPECT/CT for visualization of prostate cancer is safe but hampered by an unexpected low in vivo metabolic stability in man. The difference between the excellent in vitro stability of 99mTc-HABBN in human serum samples determined in our previous study regarding 99mTc-HABBN and the low in vivo metabolic stability determined in this study, is striking. This issue warrants further study of peptide-based radiopharmaceuticals.
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Authors
Hildo J.K. Ananias, Zilin Yu, Hilde D. Hoving, Stefano Rosati, Rudi A. Dierckx, Fan Wang, Yongjun Yan, Xiaoyuan Chen, Jan Pruim, Marjolijn N. Lub-de Hooge, Wijnand Helfrich, Philip H. Elsinga, Igle J. de Jong,