Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10916064 | Nuclear Medicine and Biology | 2013 | 6 Pages |
Abstract
Rilotumumab inhibited 18Â F-FDG and 18Â F-FLT accumulation as early as 2 and 4Â days after treatment, respectively, in a mouse tumor model. Further studies to evaluate 18Â F-FDG PET imaging as an early tumor response marker for rilotumumab are warranted. Rilotumumab is currently being tested in patients with MET-positive, advanced gastric and gastroesophageal cancer.
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Authors
Karen Rex, Xiaoman Z. Lewis, Sundaresan Gobalakrishnan, Charles Glaus, Matthew D. Silva, Robert Radinsky, Teresa L. Burgess, Sanjiv S. Gambhir, Angela Coxon,