| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10916070 | Nuclear Medicine and Biology | 2013 | 11 Pages |
Abstract
[99mTc]O2-AMD3100 is readily labelled, is stable in plasma and displays a favourable binding affinity for the CXCR4 receptors. [99mTc O2-AMD3100 shows specific binding in organs with high CXCR4 expression and in CXCR4 positive tumors. These results justify further evaluation of this radiopharmaceutical as a potential biomarker for the non-invasive imaging of CXCR4 receptors.
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Authors
Siddesh V. Hartimath, Urszula M. Domanska, Annemiek M.E. Walenkamp, Rudi A.J.O. Dierckx, Erik F.J. de Vries,