Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10916117 | Nuclear Medicine and Biology | 2011 | 6 Pages |
Abstract
Our results indicated that an improved transgene expression of 131I-stimulated hNIS in U87 cells using a baculovirus vector containing the Egr1 promoter is possible, and the increased expression of hNIS is responsible for a higher 131I uptake. It might provide a reference for the existence of a positive feedback effect in 131I-promoted Bac-Egr1-hNIS expression in malignant glioma and is an interesting aspect of NIS-related studies.
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Authors
Rui Guo, Lipeng Tian, Bing Han, Haoping Xu, Miao Zhang, Biao Li,