Article ID Journal Published Year Pages File Type
10916831 Pathology - Research and Practice 2016 7 Pages PDF
Abstract
Our study shows an increased expression of MnSOD in anaplastic astrocytoma and GBM compared to low grade astrocytoma and control brain. An increase in MnSOD expression following GBM tumor recurrence strengthens its putative role in tumor aggressiveness. Further, MnSOD emerges as a poor prognostic biomarker in p53 expressing GBMs, rendering this molecule as a potential therapeutic target in such patients.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Preview
Manganese superoxide dismutase (MnSOD) is a malignant astrocytoma specific biomarker and associated with adverse prognosis in p53 expressing glioblastoma
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