Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10917824 | Radiotherapy and Oncology | 2016 | 8 Pages |
Abstract
Serial MRI acquisitions enable the identification of both early and late radiation-induced changes in swallowing structures after definitive IMRT for NPC. Dose dependent decrease in late T1 SI is associated with higher RT doses to the superior pharyngeal constrictor muscle; while dose independent increase in SI for both structures in early post-RT T2 images is observed and subsides after therapy. Further efforts will seek to elucidate the relationship between dose-dependent muscle SI changes and functional alteration of swallowing muscles.
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Authors
Jay A. Messer, Abdallah S.R. Mohamed, Katherine A. Hutcheson, Yao Ding, Jan S. Lewin, Jihong Wang, Stephen Y. Lai, Steven J. Frank, Adam S. Garden, Vlad Sandulache, Hillary Eichelberger, Chloe C. French, Rivka R. Colen, Jack Phan,