Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10917912 | Radiotherapy and Oncology | 2015 | 7 Pages |
Abstract
Our data indicate that IDH1R132H mutation causes both a less aggressive biological behavior and direct radiosensitization of human malignant glioma cells. Targeting IDH1 appears to be an attractive approach in combination with radiotherapy.
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Authors
Jacqueline Kessler, Antje Güttler, Henri Wichmann, Swetlana Rot, Matthias Kappler, Matthias Bache, Dirk Vordermark,