| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10917919 | Radiotherapy and Oncology | 2015 | 8 Pages |
Abstract
We have established a powerful, quantitative phosphoproteomic approach to investigate regulatory mechanisms in DSB repair, dependent on protein phosphorylation after irradiation. Using this approach we have identified PARP1 as a mediator of EGFR/MEK-dependent regulation of DSB repair.
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Authors
Laura Myllynen, Marcel Kwiatkowski, Lisa GleiÃner, Britta Riepen, Konstantin Hoffer, Marcus Wurlitzer, Cordula Petersen, Ekkehard Dikomey, Kai Rothkamm, Hartmut Schlüter, Malte Kriegs,