Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10917927 | Radiotherapy and Oncology | 2015 | 7 Pages |
Abstract
A novel clinically applicable method to quantify residual γH2AX foci in ex vivo irradiated tumour samples was established. The first clinical results suggest that this method allows to distinguish between radiosensitive and radioresistant tumour types. These findings support further translational evaluation of this assay to individualise radiation therapy.
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Authors
Apostolos Menegakis, Cläre von Neubeck, Ala Yaromina, Howard Thames, Sandra Hering, Joerg Hennenlotter, Marcus Scharpf, Susan Noell, Mechthild Krause, Daniel Zips, Michael Baumann,