Dose to the non-involved uterine corpus with MRI guided brachytherapy in locally advanced cervical cancer

MRI guided dose optimisation lowered the dose to the uterine corpus. However, a total EBRT + BT dose larger than 50 Gy was obtained in 99% of patients. Assuming that 45-50 Gy is sufficient to eradicate microscopic disease, the lowering of uterus corpus dose is not expected to induce additional uterine corpus recurrences in the setting of MRI guided adaptive BT. This hypothesis should be tested in a larger number of patients as e.g. the EMBRACE study.