Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10918759 | Radiotherapy and Oncology | 2013 | 5 Pages |
Abstract
In women who have undergone WLE of breast cancer with full-thickness closure of the excision cavity and who are proceeding to PBI or breast boost RT, target volume delineation based on 0 or 1 implanted markers is not recommended as large additional margins are required to account for uncertainty over true TB location. Five implanted markers (one deep and four radial) are likely to be adequate assuming the addition of a standard 10-15Â mm TB-CTV margin. Low CLI values for all TB volumes reflect the sensitivity of low volumes to small differences in delineation and are unlikely to be clinically significant for TB5M and TB6M in the context of adequate TB-CTV margins.
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Authors
Anna M. Kirby, Rajesh Jena, Emma J. Harris, Phil M. Evans, Clare Crowley, Deborah L. Gregory, Charlotte E. Coles,