Article ID Journal Published Year Pages File Type
10919031 Radiotherapy and Oncology 2012 7 Pages PDF
Abstract
The study showed a significant negative impact of smoking during radiotherapy for head and neck cancer and the risk of death was increased with each additional pack year of smoking. The effect on loco-regional control could be explained by a rise in carboxyhemoglobin level in smokers, e.g. a reduced oxygen supply to tumors. The data strongly advocate that smoking should be avoided in order to improve the therapeutic efficacy of radiotherapy and development of other smoking-related diseases and/or secondary cancers.
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Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
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