| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10919339 | Radiotherapy and Oncology | 2013 | 7 Pages |
Abstract
Despite the lack of direct cellular radiosensitisation, PLK1 inhibition with BI 6727 during fractionated irradiation significantly improves local tumour control when compared to irradiation alone. This result is likely explained by a considerable effect on cell cycle and an independent cytotoxic potential of BI 6727.
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Authors
Mechthild Krause, Berit Kummer, Andre Deparade, Wolfgang Eicheler, Dorothee Pfitzmann, Ala Yaromina, Leoni A. Kunz-Schughart, Michael Baumann,