Article ID Journal Published Year Pages File Type
10919341 Radiotherapy and Oncology 2013 5 Pages PDF
Abstract
PAN acts as a radiosensitiser in bladder cancer cell lines, and appears to target HR rather than NHEJ. As muscle-invasive bladder tumours have reduced Ku-DNA binding, PAN could be particularly useful as a radiosensitiser in bladder cancer.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Preview
Radiosensitisation of bladder cancer cells by panobinostat is modulated by Ku80 expression
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