Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10919344 | Radiotherapy and Oncology | 2013 | 6 Pages |
Abstract
We demonstrate an important role for NOTCH in tumor growth and correlate high NOTCH activity with poor prognosis and radioresistance. Blocking NOTCH activity in NSCLC might be a promising intervention to improve outcome after radiotherapy.
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Authors
Jan Theys, Sanaz Yahyanejad, Roger Habets, Paul Span, Ludwig Dubois, Kim Paesmans, Bo Kattenbeld, Jack Cleutjens, Arjan J. Groot, Olga C.J. Schuurbiers, Philippe Lambin, Jan Bussink, Marc Vooijs,