Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10919347 | Radiotherapy and Oncology | 2013 | 7 Pages |
Abstract
This is the first report of a miRNA expression signature for in vitro chemoradiosensitivity of CRC cell lines. Many of the identified miRNAs have not been linked to the response to CRT and may represent potential molecular targets to sensitize resistant cancers. If further validated, let7g expression may serve as predictive biomarker.
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Authors
Junius Salendo, Melanie Spitzner, Frank Kramer, Xin Zhang, Peter Jo, Hendrik A. Wolff, Julia Kitz, Silke KaulfuÃ, Tim BeiÃbarth, Matthias Dobbelstein, Michael Ghadimi, Marian Grade, Jochen Gaedcke,