Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10919371 | Radiotherapy and Oncology | 2013 | 7 Pages |
Abstract
Our results demonstrate that IRE1α but not its splicing activity is important for hypoxic cell survival. The PERK signaling arm is uniquely important for promoting adaptation and survival during hypoxia-induced ER stress and should be the focus of future therapeutic efforts.
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Authors
Dan Cojocari, Ravi N. Vellanki, Brandon Sit, David Uehling, Marianne Koritzinsky, Bradly G. Wouters,