| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10919393 | Radiotherapy and Oncology | 2011 | 7 Pages |
Abstract
The dominant negative mutant Artemis fragment (D37N-413aa) enhanced tumor cell radiosensitivity through blocking activity of endogenous Artemis and DNA repair. It is the first time to modulate tumor cell radiosensitivity via targeting Artemis. This novel mechanism of radiosensitivity strongly suggests the potential role of Artemis in cancer therapy.
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Authors
Hai Liu, XiaoNan Sun, Shuo Zhang, WeiTing Ge, YongLiang Zhu, JiaWei Zhang, Shu Zheng,