Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10919559 | Radiotherapy and Oncology | 2013 | 7 Pages |
Abstract
The high fidelity of HR, which is independent of induced DNA damage level, is postulated to explain the low fractionation sensitivity and cellular resistance of cells in S/G2 phase. In conclusion, our results suggest that HR mediates resistance to fractionated radiotherapy, an observation that may help future efforts to improve radiotherapy outcome.
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Authors
Navita Somaiah, John Yarnold, Anne Lagerqvist, Kai Rothkamm, Thomas Helleday,