| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 10919652 | Radiotherapy and Oncology | 2011 | 4 Pages |
Abstract
The number of circulating CD34+ (hematopoietic stem) cells (HSCs) was observed to decline by 15% in breast cancer patients after starting adjuvant radiation therapy, regardless of age or preceding chemotherapy. These data demonstrate that local radiation therapy can profoundly affect HSC homeostasis, which might have a myriad of important implications.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Nehad M. Alajez, Wei Wang, Debashis Biswas, Amy Teh, Robert Sutherland, Melania Pintilie, Mark Minden, Hans Messner, Anthony Fyles, Mary Gospodarowicz, Armand Keating, Fei-Fei Liu,