Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10919746 | Radiotherapy and Oncology | 2011 | 6 Pages |
Abstract
The higher radiation resistance in clone CE8 is likely due to NNMT overexpression. The higher levels of NNMT could affect the cellular damage resistance through depletion of the accessible amounts of nicotinamide, which is a known inhibitor of cellular DNA repair mechanisms.
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Authors
Filippo P. D'Andrea, Akmal Safwat, Moustapha Kassem, Laurant Gautier, Jens Overgaard, Michael R. Horsman,