Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
10919756 | Radiotherapy and Oncology | 2011 | 8 Pages |
Abstract
In summary, our data show that CHC is able to influence the intratumoral distribution of glucose use between hypoxic and non-hypoxic tumor areas. That is in accordance with a functional tumor lactate-shuttle, but the absence of any detectable changes in hypoxic extent and tissue metabolites was unexpected and warrants further investigation.
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Authors
Morten Busk, Stefan Walenta, Wolfgang Mueller-Klieser, Torben Steiniche, Steen Jakobsen, Michael Robert Horsman, Jens Overgaard,